性能参数

产品名称

(±)9(10)-DiHOME

规格

25μg 50μg 100μg 500μg

货号

GOY-Y0017

 含量

>98.00%

CAS

263399-34-4

别名

N/A

化学名

N/A

分子式

C18H34O4

分子量

分子 314.5

溶解度

DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 10 μ g/ml

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

用途

仅供科研

价格

电询

详细内容

Leukotoxin is the 9(10) epoxide of linoleic acid, generated by neutrophils during the oxidative burst. This unstable compound is rapidly degraded by epoxide hydrolases to form the diol, (±)9(10)-DiHOME. Mitochondrial dysfunction, vasodilation, and apoptosis are features of leukotoxin toxicity. In renal proximal tubular cells, the diol hydrolysis products of leukotoxin, such as (±)9(10)-DiHOME, have been directly implicated as the cytotoxic agent responsible for cell death.

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