(3S)-hydroxy Quinidine
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产品名称:
(3S)-hydroxy Quinidine
产品型号:
GOY-Y0030
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-07
简单介绍
(3S)-hydroxy QuinidineMethanol: Soluble
(3S)-hydroxy Quinidine
的详细介绍
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性能参数
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产品名称
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(3S)-hydroxy Quinidine
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规格
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500μg 1mg
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货号
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GOY-Y0030
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含量
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>98.00%
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CAS
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53467-23-5
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别名
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N/A
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化学名
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N/A
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分子式
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C20H24N2O3
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分子量
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分子 340.4
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溶解度
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Methanol: Soluble
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储存条件
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Store at -20°C
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General tips
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General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
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用途
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仅供科研
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价格
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电询
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详细内容
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(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.
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