1-Methylnicotinamide (chloride)
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产品名称:
1-Methylnicotinamide (chloride)
产品型号:
GOY-Y0096
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-07
简单介绍
1-Methylnicotinamide (chloride)10mg/ml in PBS (pH 7.2)
1-Methylnicotinamide (chloride)
的详细介绍
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性能参数
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产品名称
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1-Methylnicotinamide (chloride)
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规格
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100mg 500mg 1g
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货号
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GOY-Y0096
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含量
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>98.00%
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CAS
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1005-24-9
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别名
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N/A
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化学名
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N/A
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分子式
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C7H9N2O?Cl
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分子量
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分子 172.6
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溶解度
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10mg/ml in PBS (pH 7.2)
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储存条件
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Store at -20°C
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General tips
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General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
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用途
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仅供科研
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价格
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电询
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详细内容
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Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase . It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.
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