14,15-dehydro Leukotriene B4
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产品名称:
14,15-dehydro Leukotriene B4
产品型号:
GOY-Y0135
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-07
简单介绍
14,15-dehydro Leukotriene B4DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): >1 mg/ml
14,15-dehydro Leukotriene B4
的详细介绍
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性能参数
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产品名称
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14,15-dehydro Leukotriene B4
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规格
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25μg 50μg 100μg
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货号
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GOY-Y0135
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含量
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>97.00%
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CAS
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114616-11-4
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别名
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N/A
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化学名
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N/A
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分子式
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C20H30O4
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分子量
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分子 334.5
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溶解度
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DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): >1 mg/ml
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储存条件
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Store at -20°C
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General tips
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General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
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用途
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仅供科研
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价格
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电询
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详细内容
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Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM. 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 μM.
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