2',2'-Difluoro-2'-deoxyuridine
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产品名称:
2',2'-Difluoro-2'-deoxyuridine
产品型号:
GOY-Y0164
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-07
简单介绍
2',2'-Difluoro-2'-deoxyuridineDMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml
2',2'-Difluoro-2'-deoxyuridine
的详细介绍
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性能参数
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产品名称
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2',2'-Difluoro-2'-deoxyuridine
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规格
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1mg 5mg 10mg 25mg
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货号
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GOY-Y0164
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含量
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>95.00%
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CAS
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114248-23-6
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别名
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N/A
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化学名
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N/A
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分子式
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C9H10F2N2O5
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分子量
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分子 264.2
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溶解度
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DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml
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储存条件
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Store at -20°C
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General tips
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General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
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用途
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仅供科研
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价格
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电询
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详细内容
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2',2'-Difluoro-2'-deoxyuridine is an active metabolite of the anticancer nucleoside analog gemcitabine .1 It is formed by deamination of gemcitabine by cytidine deaminase in the liver. 2',2'-Difluoro-2'-deoxyuridine is cytotoxic to HepG2 and A549 cancer cells (IC50s = 3.13 and 3.92 μM, respectively). It enhances radiation-induced cell death of ECV304 and NCI H292 cells when used at concentrations ranging from 10 to 100 μM.2
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