20-hydroxy Leukotriene B4
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产品名称:
20-hydroxy Leukotriene B4
产品型号:
GOY-Y0218
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
20-hydroxy Leukotriene B4DMF: >50 mg/ml (per Rao Maddipati),DMSO: >50 mg/ml (per Rao Maddipati),Ethanol: >50 mg/ml (per Rao Maddipati),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)
20-hydroxy Leukotriene B4
的详细介绍
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性能参数
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产品名称
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20-hydroxy Leukotriene B4
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规格
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25μg 50μg 100μg
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货号
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GOY-Y0218
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含量
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>97.00%
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CAS
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79516-82-8
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别名
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N/A
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化学名
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N/A
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分子式
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C20H32O5
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分子量
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分子 352.5
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溶解度
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DMF: >50 mg/ml (per Rao Maddipati),DMSO: >50 mg/ml (per Rao Maddipati),Ethanol: >50 mg/ml (per Rao Maddipati),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)
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储存条件
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Store at -20°C
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General tips
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General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
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用途
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仅供科研
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价格
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电询
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详细内容
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20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2 receptor, but does not appear to function as an agonist.
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