性能参数

产品名称

3-Hydroxycoumarin

规格

5g

货号

GOY-Y0261

 含量

>95.00%

CAS

939-19-5

别名

N/A

化学名

N/A

分子式

C9H6O3

分子量

分子 162.1

溶解度

DMF: 15 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

3-Hydroxycoumarin is a coumarin that has been found in A. reinwardtii and has diverse biological activities.1,2,3 It inhibits 15-lipoxygenase-1 (15-LO-1; IC50 = 9.5 μM).1 3-hydroxycoumarin scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM) and inhibits lipid peroxidation in vitro (IC50 = 69.07 mM).2 It is protective against UVB-induced embryotoxicity in sea urchins (E. lucunter).3

1.Alavi, S.J., Sadeghian, H., Seyedi, S.M., et al.A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarinChem. Biol. Drug Des.91(6)1125-1132(2017) 2.Rattanapan, J., Sichaem, J., and Tip-pyang, S.Chemical constituents and antioxidant activity from the stems of Alyxia reinwardtiiRec. Nat. Prod.6(3)288-291(2012) 3.de Araujo Leite, J.C., de Castro, T.M.X., Barbosa-Filho, J.M., et al.Photoprotective effect of coumarin and 3-hydroxycoumarin in sea urchin gametes and embryonic cellsJ. Photochem. Photobiol. B Biol.14644-51(2015)

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