性能参数

产品名称

3-Phenyltoxoflavin

规格

5g  10mg  25mg  50mg  100mg

货号

GOY-Y0303

 含量

>99.00%

CAS

32502-63-9

别名

N/A

化学名

N/A

分子式

C13H11N5O2

分子量

分子 269.26

溶解度

DMSO: 7.14 mg/mL (26.52 mM)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

3-Phenyltoxoflavin, a derivative of Toxoflavin, is an Hsp90 inhibitor, with a Kd of 585 nM for the interaction of Hsp90-TPR2A. 3-Phenyltoxoflavin has anti-cancer activity[1][2].

3-Phenyltoxoflavin (1 nM-100 μM; 4 d) inhibits BT474 cells proliferation in a concentration-dependent manner, with an IC50 of 690 nM[1].3-Phenyltoxoflavin (0.56 nM-100 μM; 2 h) competes with biotinylated Hsp90 peptide for its binding to TPR2A in a dose-dependent manner[1].

[1]. Yi F, et, al. A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol. 2008 Oct 17;3(10):645-54. [2]. Koh S, et, al. A novel light-dependent selection marker system in plants. Plant Biotechnol J. 2011 Apr;9(3):348-58.

长春氟宁 规格： HPLC≥98%;20mg

奥瑞布林 规格： HPLC≥98%;20mg

β-拉帕醌 规格： HPLC≥98%;5mg

5,6-二甲基呫吨酮-4-乙酸 规格： HPLC≥98%;20mg

4-甲基伞形酮（羟甲香素） 规格： HPLC≥98%;20mg

TPI-287 规格： HPLC≥98%;20mg

4-(三氟甲基)苯肼4-(Trifluoromethyl)phenylhydrazine,96%368-90-11G

(2-羟乙基)肼2-Hydroxyethylhydrazine,≥98.0%109-84-210ML

丁酰肼Daminozide,99%1596-84-525G

二苯偶氮碳酰肼Diphenylcarbazone,60%538-62-55G

乙酰苯肼1-Acetyl-2-phenylhydrazine,≥98%114-83-025G

盐酸联氨Hydrazine dihydrochloride,≥98%5341-61-725G