3β-hydroxy-5-Cholestenoic Acid
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产品名称:
3β-hydroxy-5-Cholestenoic Acid
产品型号:
GOY-Y0306
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
3β-hydroxy-5-Cholestenoic AcidSoluble in DMSO
3β-hydroxy-5-Cholestenoic Acid
的详细介绍
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性能参数
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产品名称
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3β-hydroxy-5-Cholestenoic Acid
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规格
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500μg 1mg
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货号
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GOY-Y0306
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含量
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>98.00%
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CAS
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6561-58-6
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别名
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N/A
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化学名
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(3β)-3-hydroxy-cholest-5-en-26-oic acid
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分子式
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C27H44O3
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分子量
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分子 416.6
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溶解度
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Soluble in DMSO
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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3β-hydroxy-5-Cholestenoic acid is an active metabolite of cholesterol formed when cholesterol is metabolized by the cytochrome P450 (CYP) isomer CYP27A1. 3β-hydroxy-5-Cholestenoic acid is a modulator of γ-secretase that decreases amyloid β (1-42) peptide (Aβ42; EC50 = 250 nM) and increases Aβ38 levels with no effect on total Aβ in CHO2B7 cells. It decreases endogenous murine Aβ42 production by 60 and 75% in mouse postnatal neuron-glia cultures at concentrations of 3 and 10 μM, respectively.
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