4’-hydroxy Trazodone
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产品名称:
4’-hydroxy Trazodone
产品型号:
GOY-Y0308
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
4’-hydroxy TrazodoneChloroform: slightly soluble,Methanol: slightly, sonicated
4’-hydroxy Trazodone
的详细介绍
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性能参数
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产品名称
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4’-hydroxy Trazodone
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规格
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1mg
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货号
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GOY-Y0308
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含量
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>95.00%
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CAS
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53818-10-3
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别名
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N/A
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化学名
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N/A
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分子式
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C19H22ClN5O2
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分子量
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分子 387.9
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溶解度
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Chloroform: slightly soluble,Methanol: slightly, sonicated
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1 It is an inhibitor of organic anion transporter 3 (OAT3; Ki = 16.9 μM) and is selective for OAT3 over OAT1 (Ki = >200 μM).2
1.Yamato, C., Takahashi, T., Fujita, T., et al.Studies on metabolism of trazodone, II. Metabolic fate after intravenous administration and effects on liver microsomal drug-metabolizing enzymes in ratsXenobiotica4(12)765-777(1974) 2.Zou, L., Matsson, P., Stecula, A., et al.Drug metabolites potently inhibit renal organic anion transporters, OAT1 and OAT3J. Pharm. Sci.110(1)347-353(2021)
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