性能参数

产品名称

4-Chlorophenylguanidine hydrochloride

规格

100mg

货号

GOY-Y0325

 含量

>98.00%

CAS

14279-91-5

别名

N/A

化学名

N/A

分子式

C7H8ClN3.HCl

分子量

分子 206.07

溶解度

Soluble to 100 mM in H2O

储存条件

Store at RT

General tips

用途

仅供科研

价格

电询

详细内容

4-Chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase [1].

Urokinase is a serine protease. Its primary physiological substrate is plasminogen, which is an inactive form of plasmin. Urokinase plays an important role in vascular diseases and cancer.

4-Chlorophenylguanidine hydrochloride inhibited urokinase and trypsin with Ki value of 6.07 μM and 120 μM, respectively [1].

Reference:

[1].  Yang H, Henkin J, Kim KH, et al. Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. J Med Chem, 1990, 33(11): 2956-2961.

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