4-Hydroxyphenylacetic acid
如果您对该产品感兴趣的话,可以
产品名称:
4-Hydroxyphenylacetic acid
产品型号:
GOY-Y0332
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
4-Hydroxyphenylacetic acidDMSO : ≥ 100 mg/mL (657.25 mM)
4-Hydroxyphenylacetic acid
的详细介绍
|
性能参数
|
|
产品名称
|
4-Hydroxyphenylacetic acid
|
|
规格
|
100mg
|
|
货号
|
GOY-Y0332
|
|
含量
|
>98.00%
|
|
CAS
|
156-38-7
|
|
别名
|
N/A
|
|
|
|
化学名
|
N/A
|
分子式
|
C8H8O3
|
|
分子量
|
分子 152.15
|
溶解度
|
DMSO : ≥ 100 mg/mL (657.25 mM)
|
|
储存条件
|
Store at -20°C
|
General tips
|
|
|
用途
|
仅供科研
|
价格
|
电询
|
|
|
|
详细内容
|
4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[1].
4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1[1].
[1]. Zhao H, et al. 4-Hydroxyphenylacetic Acid Prevents Acute APAP-Induced Liver Injury by Increasing Phase IIand Antioxidant Enzymes in Mice. Front Pharmacol. 2018 Jun 19;9:653.
|
公司正在销售的产品：
|
香蜂草苷 规格： HPLC≥98%;20mg
香紫苏内酯 规格： HPLC≥98%;20mg
胸腺五肽 规格： HPLC≥98%;50mg
香兰素 规格： HPLC≥98%;20mg
消旋山莨菪碱 规格： HPLC≥98%;20mg
卫矛醇 规格： HPLC≥98%; 20mg
|
2-氯烟酰氯2-Chloronicotinoyl chloride,98%49609-84-95G
乙酰溴Acetyl bromide,99%506-96-725G
过氧化十二酰Lauroyl peroxide,97105-74-825G
叠氮磷酸二苯酯Diphenyl phosphoryl azide,97%26386-88-95G
过氧化苯甲酰Benzoyl peroxide,75%94-36-0100G
苯偶酰Benzil,98%134-81-6100G
|