4-Ethynyl-L-phenylalanine hydrochloride
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产品名称:
4-Ethynyl-L-phenylalanine hydrochloride
产品型号:
GOY-Y0338
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
4-Ethynyl-L-phenylalanine hydrochlorideMethanol: 125 mg/mL (553.91 mM); DMSO: 100 mg/mL (443.12 mM); H2O: < 0.1 mg/mL (insoluble)
4-Ethynyl-L-phenylalanine hydrochloride
的详细介绍
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性能参数
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产品名称
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4-Ethynyl-L-phenylalanine hydrochloride
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规格
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10mM*1 mL 50mg
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货号
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GOY-Y0338
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含量
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>99.00%
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CAS
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188640-63-3
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别名
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N/A
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化学名
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N/A
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分子式
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C11H12ClNO2
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分子量
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分子 225.67
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溶解度
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Methanol: 125 mg/mL (553.91 mM); DMSO: 100 mg/mL (443.12 mM); H2O: < 0.1 mg/mL (insoluble)
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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4-Ethynyl-L-phenylalanine hydrochloride is a selective, reversible, potent and competitive inhibitor of tryptophan hydroxylase (TPH). 4-Ethynyl-L-phenylalanine hydrochloride is a competitive inhibitor with regard to the substrate tryptophan, with a Ki of 32.6 μM. 4-Ethynyl-L-phenylalanine hydrochloride selectively and reversibly inhibits the biosynthesis of serotonin[1].
4-Ethynyl-L-phenylalanine hydrochloride (30 mg/kg; i.p.) decreases in 5-HT and 5-HIAA levels in the rat midbrain but not in tissue[1].4-Ethynyl-L-phenylalanine hydrochloride is not inhibiting the aromatic amino acid decarboxylase[1].4-Ethynyl-L-phenylalanine hydrochloride has a low affinity for various recombinant 5-HT receptors[1]. Animal Model: Male Sprague-Dawley rats (200 g)[1]
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