性能参数

产品名称

4-hydroxy Atorvastatin lactone

规格

1mg

货号

GOY-Y0343

 含量

>95.00%

CAS

163217-70-7

别名

N/A

化学名

5-(4-fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide

分子式

C33H33FN2O5

分子量

分子 556.6

溶解度

DMSO: Soluble,Methanol: Slightly soluble

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin and 2-hydroxy atorvastatin, which can be interconverted between their acid and lactone forms. Atorvastatin can itself be lactonized to atorvastatin lactone then metabolized by CYP3A4 directly to 4-hydroxy atorvastatin lactone and 2-hydroxy atorvastatin lactone.

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水甘草碱 规格： HPLC≥98%;20mg

沙蟾毒精 规格： HPLC≥98%;20mg

三十烷醇 规格： HPLC≥98%;20mg

苏丹红Ⅳ 规格： HPLC≥98%;20mg

苏丹红Ⅲ 规格： HPLC≥98%;20mg

苯并呋喃2,3-Benzofuran,99%271-89-65G

2,3-二氢呋喃2,3-Dihydrofuran,99%1191-99-725ML

3,4-二氢-2H-吡喃3,4-Dihydro-2H-pyran,97%110-87-2100ML

2,5-二甲基呋喃2,5-Dimethylfuran,99%625-86-525ML

2,5-二甲氧基四氢呋喃2,5-Dimethoxytetrahydrofuran,98%696-59-325G

2-乙酰-5-甲基呋喃2-Acetyl-5-methylfuran,98%1193-79-95G