4-Methylamino antipyrine
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产品名称:
4-Methylamino antipyrine
产品型号:
GOY-Y0365
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
4-Methylamino antipyrineSoluble in DMSO
4-Methylamino antipyrine
的详细介绍
性能参数
产品名称
4-Methylamino antipyrine
规格
10mg 25mg
货号
GOY-Y0365
含量
>98.00%
CAS
519-98-2
别名
N/A
化学名
N/A
分子式
C12H15N3O
分子量
分子 217.27
溶解度
Soluble in DMSO
储存条件
Store at -20°C
General tips
用途
仅供科研
价格
电询
详细内容
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic drug and can be used for pain and fever[1][2][3]. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties[2].
[1]. Burmańczuk A, et al. Pharmacokinetic investigations of the marker active metabolites 4-methylamino-antipyrine and 4-amino-antipyrine after intramuscular injection of metamizole in healthy piglets. J Vet Pharmacol Ther. 2016 Dec;39(6):616-620. [2]. Campos C1, et al. Regulation of cyclooxygenase activity by metamizol. Eur J Pharmacol. 1999 Aug 13;378(3):339-47. [3]. Ariza A, et al. Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole. Sci Rep. 2016 Mar 31;6:23845.
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