5,6-dihydro-5-Fluorouracil
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产品名称:
5,6-dihydro-5-Fluorouracil
产品型号:
GOY-Y0371
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
5,6-dihydro-5-FluorouracilDMF: 60 mg/ml,DMSO: 53 mg/ml,Ethanol: 0.8 mg/ml,PBS (pH 7.2): 8 mg/ml
5,6-dihydro-5-Fluorouracil
的详细介绍
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性能参数
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产品名称
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5,6-dihydro-5-Fluorouracil
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规格
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5mg 10mg 25mg 50mg
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货号
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GOY-Y0371
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含量
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>95.00%
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CAS
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696-06-0
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别名
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N/A
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化学名
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5-fluorodihydro-2,4(1H,3H)-pyrimidinedione
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分子式
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C4H5FN2O2
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分子量
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分子 132.1
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溶解度
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DMF: 60 mg/ml,DMSO: 53 mg/ml,Ethanol: 0.8 mg/ml,PBS (pH 7.2): 8 mg/ml
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD). Formulations containing 5-FU are used for the treatment of cancer. However, in patients lacking full DPD activity, severe adverse events, including death, can occur. 5-FUH2 is less toxic than 5-FU but is not as effective (IC50s = 3.3 and 560 uM for 5-FU and 5-FUH2, respectively in WiDr human colon cancer cells).
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