5-Aminovaleric acid hydrochloride
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产品名称:
5-Aminovaleric acid hydrochloride
产品型号:
GOY-Y0398
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
5-Aminovaleric acid hydrochlorideSoluble in DMSO
5-Aminovaleric acid hydrochloride
的详细介绍
性能参数
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产品名称
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5-Aminovaleric acid hydrochloride
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规格
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5g 25g
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货号
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GOY-Y0398
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含量
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>98.00%
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CAS
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660-88-8
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别名
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5-aminopentanoic acid
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化学名
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分子式
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C5H11NO2
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分子量
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分子 117.15
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溶解度
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Soluble in DMSO
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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5-Aminovaleric acid has been identified as an important five-carbon platform chemical, which can be used for the synthesis of polymers and other chemicals of industrial interest as well.
In vitro: 5-Aminovaleric acid, a GABA analog, was reported to be able to inhibit GABA uptake, inactivate GABA aminotransferase, and could also both agonize and antagonize GABAb receptors. In addition, 5-aminovaleric acid has been found to be able to increase glutamine concentrations, thus possibly compensating for the decreased concentration of brain glutamine [1].
In vivo: Animal study found that 5-aminovaleric acid-treated rats showed a 3.5-fold reduction in the number of seizures than PBS-treated rats. In addition, both groups showed similar seizure frequency (~1 seizure/day). However, the fraction of the most severe type of seizures increased over time in the PBS treated group, but not in the 5-aminovaleric acid treated group. Moreover, 5-aminovaleric acid treated rats experienced a 2.3- and 2.6-fold lower fraction of stage 4 and 5 seizures than PBS-treated rats [1].
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