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5-Aminovaleric acid hydrochloride

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产品名称: 5-Aminovaleric acid hydrochloride
产品型号: GOY-Y0398
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-10

简单介绍

5-Aminovaleric acid hydrochlorideSoluble in DMSO


5-Aminovaleric acid hydrochloride  的详细介绍

性能参数

产品名称

5-Aminovaleric acid hydrochloride

规格

5g 25g

货号

GOY-Y0398

 含量

>98.00%

CAS

660-88-8

别名

5-aminopentanoic acid

 

 

化学名

 

分子式

C5H11NO2

分子量

分子 117.15

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

 

用途

仅供科研

价格

电询

详细内容

5-Aminovaleric acid has been identified as an important five-carbon platform chemical, which can be used for the synthesis of polymers and other chemicals of industrial interest as well.

In vitro: 5-Aminovaleric acid, a GABA analog, was reported to be able to inhibit GABA uptake, inactivate GABA aminotransferase, and could also both agonize and antagonize GABAb receptors. In addition, 5-aminovaleric acid has been found to be able to increase glutamine concentrations, thus possibly compensating for the decreased concentration of brain glutamine [1].

In vivo: Animal study found that 5-aminovaleric acid-treated rats showed a 3.5-fold reduction in the number of seizures than PBS-treated rats. In addition, both groups showed similar seizure frequency (~1 seizure/day). However, the fraction of the most severe type of seizures increased over time in the PBS treated group, but not in the 5-aminovaleric acid treated group. Moreover, 5-aminovaleric acid treated rats experienced a 2.3- and 2.6-fold lower fraction of stage 4 and 5 seizures than PBS-treated rats [1].

 

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