7-hydroxy Chlorpromazine (hydrochloride)
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产品名称:
7-hydroxy Chlorpromazine (hydrochloride)
产品型号:
GOY-Y0443
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-10
简单介绍
7-hydroxy Chlorpromazine (hydrochloride)Methanol: slightly soluble
7-hydroxy Chlorpromazine (hydrochloride)
的详细介绍
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性能参数
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产品名称
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7-hydroxy Chlorpromazine (hydrochloride)
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规格
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2.5mg
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货号
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GOY-Y0443
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含量
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>98.00%
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CAS
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51938-11-5
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别名
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N/A
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化学名
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N/A
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分子式
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C17H19ClN2OS?HCl
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分子量
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分子 371.3
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溶解度
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Methanol: slightly soluble
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .1 In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.2
1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977) 2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974)
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