性能参数

产品名称

Afzelin

规格

1mg 5mg

货号

GOY-Y0529

 含量

>98.00%

CAS

482-39-3

别名

N/A

化学名

N/A

分子式

C21H20O10

分子量

分子 432.38

溶解度

Ethanol: 50 mg/mL (115.64 mM)

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Afzelin (Kaempferol-3-O-rhamnoside) is is a flavonol glycoside found in Houttuynia cordata Thunberg and is widely used in the preparation of antibacterial and antipyretic agents, detoxicants and for the treatment of inflammation. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1. Afzelin improves the survival rate and reduces the serum levels of alanine aminotransferase and pro-inflammatory cytokines in D-galactosamine (GalN)/LPS -treated mice[1].

[1]. Lee SB, et al. Afzelin ameliorates D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics. Br J Pharmacol. 2017 Jan;174(2):195-209.

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