性能参数

产品名称

15-acetoxy Scirpenol

规格

1mg 5mg

货号

GOY-Y0583

 含量

>98.00%

CAS

2623-22-5

别名

4-Deacetylanguidin,NSC 267030

化学名

12,13-epoxy-trichothec-9-ene-3α,4β,15-triol, 15-acetate

分子式

C17H24O6

分子量

分子 324.4

溶解度

≤10mg/ml in methanol;10mg/ml in dichloromethane

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

15-acetoxy Scirpenol is a trichothecene mycotoxin which is produced predominantly by members of the Fusarium genus [1]. 15-acetoxy Scirpenol could induce apoptotic cell death in human Jurkat T cells. Mycotoxins of scirpenol belong to the trichothecene family which is mainly produced by the fungal species of the genus Fusarium. Acetoxylated scirpenol has very high toxicities in animals and humans. 15-acetoxy Scirpenol exhibited cytotoxicity at a lower concentration (25 ng/ml). The 50% inhibitory concentration (IC50) values of 15-acetoxy Scirpenol was 16.1 ng/ml [2]. In the Jurkat T cells treated with 50 ng/ml of 15-acetoxyscirpenol (15-MAS), the populations of externalized PS-positive and PI-negative cells were 32.0% [2].

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