17α-hydroxy Pregnenolone
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产品名称:
17α-hydroxy Pregnenolone
产品型号:
GOY-Y0584
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-11
简单介绍
17α-hydroxy Pregnenolone0.5mg/mL in DMSO
17α-hydroxy Pregnenolone
的详细介绍
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性能参数
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产品名称
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17α-hydroxy Pregnenolone
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规格
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100mg 250mg 500mg 1g
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货号
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GOY-Y0584
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含量
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>95.00%
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CAS
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387-79-1
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别名
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NSC 63853
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化学名
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3β,17-dihydroxy-pregn-5-en-20-one
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分子式
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C21H32O3
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分子量
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分子 332.5
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溶解度
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0.5mg/mL in DMSO
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone .[1] It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.[2]
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