性能参数

产品名称

2-Arachidonoyl Glycerol

规格

1mg 5mg 10mg 25mg

货号

GOY-Y0588

 含量

>95.00%

CAS

53847-30-6

别名

2-AG

化学名

(5Z,8Z,11Z,14Z)-1,3-dihydroxypropan-2-yl icosa-5,8,11,14-tetraenoate

分子式

C23H38O4

分子量

分子 378.55

溶解度

10mg/mL in DMSO, miscible in ethanol

储存条件

Store at -80°C;protect from light

General tips

用途

仅供科研

价格

电询

详细内容

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively).[1],[2],[3] Unlike arachidonoyl ethanolamide, 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol (MAG) found in rat brain.[1],[4] Formation of 2-AG is calcium-dependent and is mediated by the activities of phospholipase C (PLC) and diacylglycerol (DAG) lipase.1 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a CB1 receptor-dependent mechanism.2 2-AG is metabolized in vitro by MAG lipase and fatty acid amide hydrolase (FAAH), with MAG lipase likely being the principle metabolizing enzyme in vivo.[5]

1,2,3-Trimyristoyl-rac-glycerol CS-01Y63309 1g 5g 10g >98.00% 555-45-3

1,2,3-Trilinoleoyl-rac-glycerol CS-01Y63310 100mg 250mg 500mg 1g >95.00% 537-40-6

1,2,3-Trilinoelaidoyl-rac-glycerol CS-01Y63311 10mg 50mg 100mg >98.00% 5188-25-0

1,4-Dioxane-2,5-diol ?

鱼肝油Fish liver oil from Gadus morrhua8009-00-5250ML

棉籽油Cottonseed oil8001-29-4250ML

杏仁油Almond oil from Prunus dulcis,≥99.99%8007-69-0250ML

κ-酪蛋白κ-Casein from bovine milk9000-71-9100MG

α-酪蛋白α-Casein from bovine milk9000-71-9250MG

β-酪蛋白β-Casein from bovine milk9000-71-9250MG