性能参数
产品名称
Asp-AMS
规格
5mg 10mg 25mg
货号
GOY-Y0624
含量
>98.00%
CAS
828288-98-8
别名
N/A
化学名
分子式
C14H19N7O9S
分子量
分子 461.41
溶解度
DMSO : ≥ 100 mg/mL (216.73 mM)
储存条件
Store at -20°C
General tips
用途
仅供科研
价格
电询
详细内容
Asp-AMS, an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme.
Asp-AMS is a 500-fold stronger competitive inhibitor of the mitochondrial enzyme than aspartol-AMP (10 nM) and a 35-fold lower competitor of human and bovine cyt-AspRSs (300 nM). Asp-AMS is a strong inhibitor with Ki in the nanomolar (nM) range. Asp-AMS has also the highest inhibitory effect for the mitochondrial enzyme. Asp-AMS is the most active inhibitor with Ki values in the nanomolar range, with a stronger effect on bacterial AspRSs (E. coli and P. aeruginosa) than on human cytosolic AspRS[1].
[1]. Messmer M, et al. Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs. Biochimie. 2009 May;91(5):596-603.
公司正在销售的产品:
3-Methylindolin-2-one CS-01Y63524 100mg 200mg 500mg >98.00% 1504-06-9
3-Methyluridine CS-01Y63525 10mM*1mL 5mg >98.00% 2140-69-4
3-Methylxanthine CS-01Y63526 100mg >98.00% 1076-22-8
3-O-Ethyl-L-ascorbic acid CS-01Y63527 500 mg >98.00% 86404-04-8
3-O-methy?
芘Pyrene, ≥99.0%129-00-01G
茚Indene,≥98.0%95-13-650ML
茚满Indan,≥95.0%496-11-725ML
苊Acenaphthene,≥99.5%83-32-91G
利巴韦林Ribavirin36791-04-5100MG
辛弗林(±)-Synephrine345205G
传真号码:021-39596320 021-39921927
QQ: 3004918891 3004905818 3004901493 移动电话:18321818584 15026555973 地址:上海松江新砖公路1155号
产品均为实验试剂,仅供科研实验使用,非药品、非食品、不可用于动物及人体!