性能参数

产品名称

Bovinic acid

规格

5mg 10mg

货号

GOY-Y0747

 含量

>98.00%

CAS

2540-56-9

别名

Bovinic acid; 9Z,11E-CLA; Rumenic Acid

化学名

9Z,11E-octadecadienoic acid

分子式

C18H32O2

分子量

分子 280.45

溶解度

100mg/mL in DMSO & DMF

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Conjugated linoleic acid (CLA) refers to a family of eight geometric isomers of linoleic acid in which the two double bonds are contiguous. (The predominant form of linoleic acid in nature, 18:ω6, has double bonds at nine and 12, interrupted by a methylene carbon.) CLA is found in both meat and dairy products, but it is not found to any significant degree in plants. The predominant isomer of CLA in animal tissue is 9Z,11E; smaller amounts of 10E,12Z also occur. Various antioxidant and antitumor activities have been attributed to CLA or its downstream metabolites.[1] Reported health benefits of dietary supplementation with CLA have been attributed variously to competitive inhibition of Δ6-desaturase and/or PPARγ activation.[2]

Reference:

[1]. Shultz, T.D., Chew, B.P., Seaman, W.R., et al. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cells. Cancer Letters 63, 125-133 (1992).

[2]. Houseknecht, K.L., Vanden Heuvel, J.P., Moya-Camarena, S.Y., et al. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochemical and Biophysical Research Communications 244, 678-682 (1998).

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