性能参数

产品名称

Taraxerol

规格

1mg 5mg 10mg

货号

GOY-Y2840

 含量

>98.00%

CAS

127-22-0

别名

N/A

化学名

N/A

分子式

C30H50O

分子量

分子量 426.72

溶解度

N/A

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Taraxerol is isolated from Abroma augusta L, and has anti-inflammtory and anti-cancer effects. Taraxerol attenuates acute inlammation through inhibition of NF-κB signaling pathway. Taraxerol induces cell apoptosis[1][2].

Taraxerol (0-100 μM; 24 or 48 hours)significantly reduces cell viability to 95% (20 μM), 89.8% (40 μM), 82.6 % (60 μM), 72.9 % (80 μM), and 63.6% (100 μM).And this compound has cell viability of 90.7% at a concentration of 20 μM and 53.6% at the 100 μM concentration at 48 hours in Hela cells[1].Taraxerol (80 μM; 24 or 48 hours) induces Hela cells apoptosis and cell death in a dose-dependent manner.Taraxerol can induce a significant apoptosis of cells by annexin V/ PI double staining, significant increase in both the early (24.2%) and late (16.2%) stages of apoptotic cells compared with the control group at the early (6.5%) and late (0.5%) stages[1].

Taraxerol (5 and 10mg/kg; i.p.) attenuates carrageenan induced paw edema 2h onward. The effect of taraxerol at the dose of 5mg/kg is found to be significant (p<0.05) only after 4h of carrageenan treatment[2].

[1]. Yaoi X, et al. Taraxerol Induces Cell Apoptosis through A Mitochondria-Mediated Pathway in HeLa Cells.Cell J. 2017 Oct;19(3):512-519.

2-氯-5-氟嘧啶 97%  锗 Φ7mm高(厚)2.5mm(厚)5mm 圆柱体Ge≥99.999％

2,2-二甲基琥珀酸 98%  锗 5mm×5mm 厚2mm 正方形 Ge≥99．999％

2,2-二甲基琥珀酸酐 98%  锗 5mm 圆珠 中间穿孔 Ge≥99.999％

2,2-二氟-1,3-苯并二噁茂  95%  锗粒 99.999% metals basis，2000目

2,4-二氯-5-甲基嘧啶  98%  锗粒 99.99% metals basis,1mm

4-氟吡啶盐酸盐  98%  ?

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