性能参数

产品名称

Thapsigargin

规格

1mg 5mg 10mg

货号

GOY-Y2843

 含量

>98.00%

CAS

67526-95-8

别名

N/A

化学名

(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-(((Z)-2-methylbut-2-enoyl)oxy)-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate

分子式

C34H50O12

分子量

分子量 650.76

溶解度

30mg/ml in ethanol, DMSO, DMF

储存条件

Store at -20°C, sealed storage, away from moisture and light

General tips

用途

仅供科研

价格

电询

详细内容

In cells, sarco/endoplasmic calcium ATPases (SERCAs) transport free calcium into the sarcoplasmic and endoplasmic reticula, lowering intracellular calcium levels to stop signaling through this cation. Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC50 values are cell type-dependent and range from ~2-80 nM).1,2 Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased proliferation of certain types of cancer cells.1,3,4 In vivo, thapsigargin and related sesquiterpene lactones have anti-inflammatory and anti-cancer effects.5,6

(三氟甲基)**基硅烷 96%  硝酸铒，五水 99.9% metals basis

(三氟甲基)**基硅烷 0.5 M in THF  硫酸铒(III)八水化合物 99.9% metals basis

三乙胺三氢氟酸盐  97%  硝酸钆,六水 AR，99%

啶虫脒 分析标准品，99%  硝酸钆,六水 99.99% metals basis

杀螟丹  硝酸镓(III) 水合物 99.9% metals basis

苄嘧磺隆 分析标准品  硝酸镓(III) 水合物 99.99% metals basis

Autocamtide-2-related inhibitory peptide (TFA)1mg 5mg 10mg 50mg>98.00%Cas No. N/AC66H126N22O21F3

XRK3F25mg 10mg 50mg 100mg>98.00%Cas No. N/AC23H24ClF2NO3

VX-66110mM (in 1mL DMSO) 5mg 10mg 50mg>98.00%Cas No. 1152311-62-0C26H27F3N2O6

ULK-10110 mM * 1 mL in DMSO 2mg 5mg 10mg>98.00%Cas No. N/AC22H16F4N4OS

Bexarotene10mM (in 1mL DMSO) 10mg 50mg 100mg>98.00%Cas No. 153559-49-0C24H28O2

Bilobalide10mM (in 1mL DMSO) 25mg 50mg 100mg>98.00%Cas No. 33570-04-6C15H18O8