性能参数

产品名称

VK3-OCH3

规格

5mg 10mg 50mg

货号

GOY-Y2854

 含量

>98.00%

CAS

255906-59-3

别名

N/A

化学名

N/A

分子式

C14H14O3S

分子量

分子量 262.3

溶解度

DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 25 mg/ml,Ethanol: 5 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

VK3-OCH3 is an analog of vitamin K3 that that has antiproliferative activities in vitro. It preferentially decreases proliferation of IMR-32, LA-N-1, NB-39, and SK-N-SH neuroblastoma cells (IC50s = 2.43, 1.55, 10.69, and 3.45 μM, respectively) compared with non-cancerous HUVEC and HDF cells (IC50s = 26.24 and 87.11 μM, respectively). It increases heme oxygenase-1 (HO-1) and caveolin-1 levels, induces apoptosis, and halts the cell cycle at the G2/M phase in IMR-32 cells. VK3-OCH3 also inhibits protein-tyrosine phosphorylase (PTPase) activity (IC50 = 57.2 μM in a cell-free assay), induces protein-tyrosine phosphorylation in Hep3B hepatoma cells when used at a concentration of 50 μM, and inhibits the growth of Hep3B cells (IC50 = 8.6 μM).

氮酮 药用级  正己烷 AR，97%

富马酸二甲酯 97%  异丁酸异丁酯 98%

反丁烯二酸 CP，99.0%  甲基环己烷 Standard for GC, ≥99.8% (GC)

反丁烯二酸 99.5%  甲基环己烷 99%

反丁烯二酸 ≥99%, FCC  甲基环己烷 for HPLC,≥99%

反丁烯二酸 for cell culture，≥99%  甲基环己烷  光谱级,≥99%

ω-Agatoxin IVA10μg>98.00%Cas No. 145017-83-0C217H360N68O60S10

γ-Lindane100 mg>98.00%Cas No. 58-89-9C6H6Cl6

α-Conotoxin MII500μg>98.00%Cas No. 175735-93-0C67H103N23O22S4

(+)-Menthol100mg>98.00%Cas No. 15356-60-2C10H20O

(+)- Praeruptorin C20mg>98.00%Cas No.C22H22O7

(±)-Nipecotic acid100mg>98.00%Cas No. 60252-41-7C6H11NO2

(±)-HIP-B10mg>98.00%Cas No. 227619-65-0C6H8N2O4