性能参数

产品名称

Luteolin

规格

50mg 100mg 500mg 1g

货号

GOY-Y2868

 含量

>98.00%

CAS

491-70-3

别名

3',4',5,7-Tetrahydroxyflavone

化学名

2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one

分子式

C15H10O6

分子量

分子量 286.24

溶解度

DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:5): 1 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Luteolin (Luteolol) is a flavanoid with anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2].

Luteolin (0-160 μM; 24 hours; NCI-H460 cells) treatment inhibits the viability of NCI-H460 cells in a concentration-dependent manner[1].Luteolin (20-80 μM; 24 hours; NCI-H460 cells) treatment causes an accumulation of cells in the S phase[1].Luteolin (320-580 μM; 48 hours; NCI-H460 cells) treatment induces apoptosis[1].Luteolin (20-80 μM; 24 hours; NCI-H460 cells) treatment increases the protein expression levels of apoptotic regulatory proteins, including the Bax/Bcl-2 ratio, in a concentration-dependent manner, however, only 80 μM Luteolin inhibits the expression of Bad. Luteolin also decreases the expression of Sirt1 in the NCI-H460 cell line in a concentration-dependent manner[1].

Luteolin (10-100?mg/kg; oral gavage; daily; for 12 weeks;  male Wistar rats) has an antioxidant effect and can also protect against non-alcoholic steatohepatitis through targeting the pro-inflammatory IL-1 and Il-18 pathways in rats with a high carbohydrate/high fat diet[2].

甲基异丙基甲酮 分析标准品  氰基乙酰肼  98%

2-甲基戊烷 99%  4-羟基 99%

2-甲基戊烷 Standard for GC, ≥99% (GC)  对羟基苯乙酰胺 98%

2-甲基戊烷 82%  对羟基甲酯 99%

2-甲基戊烷 分析标准品，≥99.5% (GC)  3,4,5-**氧基苯胺 97%

异戊烯 90%  3,4,5-**氧基苯甲酰胺  98%

Kaliotoxin100μg>98.00%Cas No. 145199-73-1C171H283N55O49S8

Jujuboside A20mg>98.00%Cas No. 55466-04-1C58H94O26

L-(-)-threo-3-Hydroxyaspartic acid10mg>98.00%Cas No. 7298-99-9C4H7NO5

Lannaconitine20mg>98.00%Cas No. 32854-75-4C32H44N2O8

L-R4W21mg>98.00%Cas No. 206350-79-0C46H71N21O6

Lei-Dab 7100 ug>98.00%Cas No. 1061556-49-7C141H236N46O39S6

Mifamurtide1mg>98.00%Cas No. 83461-56-7C59H109N6O19P