性能参数

产品名称

Mocetinostat (MGCD0103, MG0103)

规格

10mM (in 1mL DMSO) 5mg 10mg 25mg

货号

GOY-Y2880

 含量

>98.00%

CAS

726169-73-9

别名

MGCD-0103

化学名

N-(2-aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamide

分子式

C23H20N6O

分子量

分子量 396.44

溶解度

≥ 19.8 mg/mL in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Mocetinostat, also known as MGCD0103 or MG0103, is an isotype-selective inhibitor of human histone deacetylases (HDAC), a family of enzymes involved in epigenetic regulation of gene transcription as well as cell proliferation, death and motility. Mocetinostat potently inhibits HDAC class I (HDAC1, HDAC2, and HDAC3) and class IV (HDAC11), with values of inhibition constant IC50 of 0.15 μmol/L, 0.29 μmol/L, 1.66 μmol/L, and 0.59 μmol/L respectively, rather than HDAC class II. Mocetinostat exerts anti-tumor activity against a broad range of human cancer cells through HDAC inhibition, in which it induces histone hyperacetylation and apoptosis and causes cell cycle blockade in a dose-dependent manner.

羟乙基纤维素 1500～2500mpa.s，25℃  乙酰丙酮(降冰片二烯)合铑 97%

羟乙基纤维素 2600～3300mpa.s，25℃  乙酰丙酮酰双(亚乙基)化铑 99%

羟乙基纤维素 5000～6400mpa.s，25℃  二羰基乙酰丙酮铑 99%

四溴化碳 98%  三苯基膦醋酸钯 Pd 14.2%

四溴化碳 99%  1,4-双(二苯基膦丁烷)二氯化钯 98%

银 99.9%，≤0.1μm  双(乙腈)氯化钯(II)  Pd 41.0%

Acamprosate calcium10 mM * 1 mL in Water 50mg>98.00%Cas No. 77337-73-6C10H20CaN2O8S2

Acacetin10mM (in 1mL DMSO) 20mg>98.00%Cas No. 480-44-4C16H12O5

AMTB hydrochloride10mg 50mg>98.00%Cas No. 926023-82-7C23H26N2O2S.HCl

Ampalex10mM (in 1mL DMSO) 100mg>98.00%Cas No. 154235-83-3C14H15N3O

Amlodipine Besylate10mM (in 1mL DMSO) 50mg>98.00%Cas No. 111470-99-6C20H25ClN2O5.C6H6O3S

Amitriptyline HCl10mM (in 1mL DMSO) 50mg>98.00%Cas No. 549-18-8C20H23N.HCl

Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride)10mM*1mLinDMSO 1g>98.00%Cas No. 2921-14-4NH2OCH2COOH · 0.5HCl