性能参数

产品名称

Periplocin

规格

1mg 5mg 10mg 50mg

货号

GOY-Y2910

 含量

>98.00%

CAS

13137-64-9

别名

N/A

化学名

N/A

分子式

C36H56O13

分子量

分子量 696.8

溶解度

DMF: 10 mg/ml,DMSO: 10 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Periplocin is a cardiac glycoside that has been isolated from P. sepium and has cardiac and anticancer activity. It increases viability and proliferation of mouse cardiac microvascular endothelial cells (CMECs) when used at concentrations ranging from 2 to 50 μM and improves left ventricular structure and function in a rat model of chronic heart failure. Periplocin inhibits cell proliferation in nine lung cancer cell lines in a time- and dose-dependent manner with IC50 values ranging from 0.12 to 53 μM. It induces apoptosis in SGC-7901 and MGC-803 gastric cancer cells and activates the ERK1/2-EGR1 pathway. Periplocin (5 and 20 mg/kg) reduces tumor growth in a hepatocellular carcinoma (HCC) mouse xenograft model. It also inhibits AKT and ERK autophosphorylation and tumor growth in an A549 lung cancer mouse xenograft model when administered at doses of 50 and 100 μg.

尿苷-5′-二磷酸二钠盐 ≥96.0% (HPLC)  (S)-(-)-2, 2-双（二对甲苯基膦）-1,1-二联萘 98%

5ˊ-尿苷酸二钠 99%   (S)-联萘(3,5-二甲苯基)膦 98%

对乙酰氨基苯酚 CP  (S,S)-DACH-苯基特罗斯特配体 95%

对乙酰氨基苯酚 AR,99.0%   (S)-N,N-二甲基-1-[(R)-1',2-双(二苯基膦基)二茂铁基]乙胺 95%

对乙酰氨基苯酚 分析标准品，≥99.5%  (S)-(-)-2-[2-(二苯基膦)苯基]-4-异丙基-2-唑啉 ?

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NBMPR10mM (in 1mL DMSO) 50mg>98.00%Cas No. 38048-32-7C17H17N5O6S

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NFPS10mg 50mg>98.00%Cas No. 405225-21-0C24H24FNO3

NF 27910mg 50mg>98.00%Cas No. 202983-32-2C49H30N6Na6O23S6