性能参数

产品名称

Pracinostat 

规格

10mM (in 1mL DMSO) 5mg 10mg 50mg

货号

GOY-Y2917

 含量

>98.00%

CAS

929016-96-6

别名

SB-939, SB 939

化学名

(E)-3-[2-butyl-1-[2-(diethylamino)ethyl]benzimidazol-5-yl]-N-hydroxyprop-2-enamide

分子式

C20H30N4O2

分子量

分子量 358.48

溶解度

≥ 11.4 mg/mL in DMSO, ≥ 24.8 mg/mL in EtOH with ultrasonic

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Pracinostat, also known as SB939, is a potent and orally available inhibitor of histone deacetylase (HDAC) with a relatively stronger selectivity (more than 1000-fold) for class I, class II and class IV HDACs rather than class III HDACs. Pracinostat potently suppresses proliferation in a wide range of cancer cell lines, including colon cancer, ovarian cancer, prostate carcinomas, acute myeloid leukaemia (AML) and B cell lymphoma. Recent study results have shown that SB939 induces the accumulation of acetylated histone H3 (AcH3) and acetylated α-tubulin and increases the expression of the cyclin dependent kinase inhibitor p21 in cancer cells.

3-氯-4-甲基苯胺 97%  三（4-三氟甲苯基）膦 99%

3-氯-4-甲基苯胺 分析标准品  三（3-甲氧基苯基）膦 97%

邻氯苯甲醛 97%  三(2,4-二甲基苯基)磷化氢-5,5',5''-三磺酸三钠盐 98%

邻氯苯甲醛 99%  三（4 -甲氧基- 3 ,5 -二甲苯基）膦 500mg

邻氯苯甲醛 Standard for GC  三（3-氯苯基）膦 98%

邻氯苯甲酸 99.0%  三（4-氯苯基）膦 98%

Penfluridol10mM (in 1mL DMSO) 50mg>98.00%Cas No. 26864-56-2C28H27ClF5NO

PD 11805710mg 50mg>98.00%Cas No. 313674-97-4C21H17Cl2NO2

α-Conotoxin ImI (trifluoroacetate salt)1 mg 5 mg 10 mg>98.00%Cas No. N/AC52H78N20O15S4·XCF3COOH

(+)-Sparteine100mg 200mg 500mg>98.00%Cas No. 492-08-0C15H26N2

(+)-MK 801 Maleate10mM (in 1mL DMSO) 10mg 50mg>98.00%Cas No. 77086-22-7C20H19NO4

(+)-MK 80110mM (in 1mL DMSO) 10mg 50mg>98.00%Cas No. 70449-94-4C16H15N

(+)-Kavain10mM*1mLinDMSO 5mg 10mg>98.00%Cas No. 500-64-1C14H14O3