Ursodeoxycholic Acid (sodium salt)
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产品名称:
Ursodeoxycholic Acid (sodium salt)
产品型号:
GOY-Y2968
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-04
简单介绍
Ursodeoxycholic Acid (sodium salt)DMF: 5 mg/ml,DMSO: 10 mg/ml,Ethanol: 15 mg/ml
Ursodeoxycholic Acid (sodium salt)
的详细介绍
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性能参数
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产品名称
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Ursodeoxycholic Acid (sodium salt)
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规格
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250mg 500mg 1g 5g
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货号
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GOY-Y2968
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含量
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>98.00%
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CAS
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2898-95-5
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别名
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N/A
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化学名
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N/A
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分子式
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C24H39O4?Na
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分子量
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分子量 414.6
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溶解度
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DMF: 5 mg/ml,DMSO: 10 mg/ml,Ethanol: 15 mg/ml
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid . UDCA is also a metabolite of lithocholic acid in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.
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