性能参数

产品名称

Pyridoclax

规格

5mg 10mg 50mg 100mg

货号

GOY-Y3243

 含量

>98.00%

CAS

Cas No.

别名

化学名

(E)-3'-methyl-3''-styryl-3,2':5',2'':5'',3'''-quaterpyridine

分子式

C29H22N4

分子量

分子量 426.51

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Pyridoclax is a potential Mcl-1 inhibitor.

Pyridoclax directly binds to Mcl-1. Without cytotoxic activity when administered as a single agent, Pyridoclax induces apoptosis in combination with Bcl-xL-targeting siRNA or with ABT-737 in ovarian, lung, and mesothelioma cancer cells[1]. Pyridoclax directly binds to Mcl-1, and hence sensitizes ovarian carcinoma cells to Bcl-xL-targeting strategies. Pyridoclax induces apoptosis in ovarian, and also in lung, and mesothelioma cancer cells when it is administrated in combination with Bcl-xL-targeting siRNA or Bcl-xL targeting molecules such as ABT-737 or its orally available derivative ABT-263[2].

4-三氟甲基水杨酸  328-90-5  1-三苯甲基咪唑-4-甲醛  33016-47-6

4-溴-1-丁醇  33036-62-3  N'-Cbz-L-鸟氨酸  3304-51-6

1H-咪唑-4,5-二甲酸二甲酯  3304-70-9  紫杉醇  33069-62-4

咖啡酸  331-39-5  3-氟-4-甲氧基溴苄  331-61-3

3,4,5-三氯吡啶  33216-52-3  2-氯-6-氰基吡啶  33252-29-8

盐酸地尔硫卓  33286-22-5  乙氧基胺盐酸盐  3332?

Fexofenadine HCl10mM (in 1mL DMSO) 10mg 50mg>99.50%Cas No. 153439-40-8C32H39NO4.HCl

FPS-ZM15mg 10mg 25mg>99.50%Cas No. 945714-67-0C20H22ClNO

Fluvoxamine maleate10mM (in 1mL DMSO) 10mg 50mg>99.50%Cas No. 61718-82-9C14H18F3N2O2.C4H4O4

Flavoxate hydrochloride10mM (in 1mL DMSO) 5mg 50mg>99.50%Cas No. 3717-88-2C24H26ClNO4

Gastrin I (human)1 mg 5 mg 10 mg>99.50%Cas No. 10047-33-3C97H124N20O31S

Granisetron HCl5mg 50mg 100mg>99.50%Cas No. 107007-99-8C18H24N4O.HCl

Glycopyrrolate10mM (in 1mL DMSO) 10mg 25mg>99.50%Cas No. 596-51-0C19H28BrNO3