性能参数

产品名称

Ziyuglycoside I

规格

20mg

货号

GOY-Y3277

 含量

>98.00%

CAS

35286-58-9

别名

化学名

分子式

C41H66O13

分子量

分子量 766.96

溶解度

≥ 76.7mg/mL in DMSO

储存条件

-20°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Ziyuglycoside I isolated from S. officinalis root, has anti-wrinkle activity, and increases the expression of type I collagen. Ziyuglycoside I could be used as an active ingredient for cosmetics[1].Ziyuglycoside I triggers cell cycle arrest and apoptosis mediated by p53, it can be a potential drug candidate for treating triple-negative breast cancer (TNBC)[2].

Ziyuglycoside I (5-160 μM; 24 hours) reveals a marked anti-proliferation activity with an IC50 value of 13.96 μM in MDA-MB-231 cells[2].Ziyuglycoside I (5-20 μM; 24 hours) induces MDA-MB-231 cell apoptosis by increasing the percentage of apoptotic cells from 2.43% to 44.76% at 20 μM[2].Ziyuglycoside I (5-20 μM; 24 hours) induces the cleavage of caspas-8, caspase-9, and caspase-3, up-regulates the pro-apoptotic protein Bax, and down-regulates anti-apoptotic protein Bal-2, dose-dependently reduces the level of mito-cyto c expression[2].

2-氯-5-氟苯胺  452-83-5  3,4-二羟基甲苯  452-86-8

氟乙酸甲酯  453-18-9  4-氟-3-硝基苯甲酸  453-71-4

哌乙酸盐  4540-33-4  **基-1,3-丙二胺  4543-96-8

3-溴-4-氯三氟甲苯  454-78-4  2-溴-5-三氟甲苯苯胺  454-79-5

3-三氟甲基苯甲醛  454-89-7  1,8-二溴辛烷  4549-32-0

对氟苯甲砜  455-15-2  3'-氟苯乙酮  455-36-7

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