性能参数

产品名称

LEESGGGLVQPGGSMK acetate

规格

5 mg 10 mg

货号

GOY-Y3293

 含量

>99.00%

CAS

N/A

别名

N/A

化学名

N/A

分子式

C66H112N18O26S

分子量

分子量 1605.76

溶解度

H2O : 100 mg/mL (62.28 mM; Need ultrasonic)

储存条件

-20°C, away from moisture

General tips

用途

仅供科研

价格

电询

详细内容

LEESGGGLVQPGGSMK acetate, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK acetate can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

[1]. Dorothée LEBERT, et al. A method for quantifying therapeutic antibodies. EP3371592A1.

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