性能参数

产品名称

Reveromycin A

规格

250μg 1mg

货号

GOY-Y3302

 含量

>99.00%

CAS

134615-37-5

别名

N/A

化学名

N/A

分子式

C36H52O11

分子量

分子量 660.8

溶解度

DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 μM.

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