Resveratrol-3-O-Sulfate (sodium salt)
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产品名称:
Resveratrol-3-O-Sulfate (sodium salt)
产品型号:
GOY-Y3366
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-05
简单介绍
Resveratrol-3-O-Sulfate (sodium salt)DMSO: Slightly Soluble
Resveratrol-3-O-Sulfate (sodium salt)
的详细介绍
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性能参数
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产品名称
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Resveratrol-3-O-Sulfate (sodium salt)
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规格
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500μg 1mg
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货号
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GOY-Y3366
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含量
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>95.00%
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CAS
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858127-11-4
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别名
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N/A
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化学名
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N/A
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分子式
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C14H11O6S?Na
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分子量
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分子量 330.3
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溶解度
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DMSO: Slightly Soluble
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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Resveratrol-3-O-sulfate is a metabolite of resveratrol . In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 μM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 μM, and induces apoptosis at concentrations of 25 and 50 μM. Resveratrol-3-O-sulfate also displaces rosiglitazone from the outer mitochondrial protein mitoNEET (IC50 = 3.36 μM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.
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