性能参数

产品名称

Acriflavine

规格

100mg

货号

GOY-Y3428

 含量

>98.00%

CAS

8048-52-0

别名

N/A

化学名

N/A

分子式

C14H14ClN3

分子量

分子量 259.73

溶解度

H2O : ≥ 25 mg/mL (96.25 mM)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Acriflavine is a fluorescent dye for labeling high molecular weight RNA. It is also a topical antiseptic.

Acriflavine is identified as a potent inhibitor of the MCT4 that can inhibit the binding between Basigin and MCT4. Acriflavine significantly inhibits growth and self-renewal potential of several glioblastoma neurosphere lines[1]. The HIF-1 inhibitor acriflavine decreases survival and growth of CML cells. It targets stem cell potential of CML cells[2].

Acriflavine treatment inhibits intratumoral expression of VEGF and tumor vascularization[1]. In a murine CML model, acriflavine decreases leukemia development and reduces LSC maintenance[2]. Acriflavine retards tumor growth in a murine model of breast cancer. The combination of sunitinib with acriflavine significantly decreases vascular endothelial growth factor and TGF-β expression and reduces tumor vasculature followed by increased intratumor necrosis and apoptosis[3].

3-甲酸  498-95-3  4-氯-2-甲基嘧啶  4994-86-9

4-羟基-3-甲基苯甲酸  499-76-3  盐酸环己胺  4998-76-9

2-溴-3‘-甲氧基苯乙酮  5000-65-7  4-吡咯烷-1-基-  1133904

环丁基甲酰氯  5006-22-4  3,5-二甲氧基苯酚  500-99-2

3-氟苯乙腈  501-00-8  白藜芦醇  501-36-0

二苯基乙炔  501-65-5  对羟基苯乙醇  501-94-0

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