Atiprimod dihydrochloride
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产品名称:
Atiprimod dihydrochloride
产品型号:
GOY-Y3429
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-08
简单介绍
Atiprimod dihydrochlorideSoluble in DMSO
Atiprimod dihydrochloride
的详细介绍
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性能参数
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产品名称
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Atiprimod dihydrochloride
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规格
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10 mg
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货号
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GOY-Y3429
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含量
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>98.00%
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CAS
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130065-61-1
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别名
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N/A
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化学名
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N/A
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分子式
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C22H44N2.2HCl
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分子量
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分子量 409.52
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溶解度
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Soluble in DMSO
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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JAK2 inhibitor (IC50 = 397 nM). Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.
Manshouri et al (2011) Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor. Cancer Res. 71 3831 PMID:21512135 |Quintás-Cardama et al (2011) Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor. Invest.New Drugs 29 818 PMID:20372971
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