性能参数

产品名称

Lys-CoA

规格

1 mg

货号

GOY-Y3444

 含量

>98.00%

CAS

N/A

别名

N/A

化学名

N/A

分子式

C31H53N10O19P3S.C2HF3O2

分子量

分子量 1108.82

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Selective p300 histone acetyltransferase (HAT) inhibitor (IC50 = 50-500 nM). Exhibits approximately 100-fold selectivity for p300 over PCAF (IC50 = 200 μM). Inhibits p300-dependent transcription. Active in vivo.

Lau et al (2000) HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. Mol.Cell. 5 589 PMID:10882143 |Liu et al (2008) The structural basis of protein acetylation by the p300/CBP transcriptional coactivator. Nature. 451 846 PMID:18273021 |Burns et al (2005) Iso-coenzyme A. J.Biol.Chem. 280 16550 PMID:15708855 |Cebrat et al (2003) Synthesis and analysis of potential prodrugs of coenzyme A analogues for the inhibition of the histone acetyltransferase p300. Bioorg.Med.Chem. 11 3307 PMID:12837541

硼酸  10043-35-3  苄基氯  100-44-7

苄胺  100-46-9  苯甲腈  100-47-0

4-氰基吡啶  100-48-1  三氯化钌  10049-08-8

环己甲醇  100-49-2  1,2,3,6-四氢苯甲醛  100-50-5

苯甲醇  100-51-6  三乙基甲基氯化铵  10052-47-8

苯甲醛  100-52-7  苄硫醇  100-53-8

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β-Casomorphin, bovine (β-Casomorphin-7 (bovine))5mg 10mg 25mg>99.50%Cas No. 72122-62-4C41H55N7O9

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