性能参数

产品名称

Nicotinamide riboside chloride

规格

10mM*1mL in Water 100mg 500mg

货号

GOY-Y3614

 含量

>98.00%

CAS

23111-00-4

别名

N/A

化学名

N/A

分子式

C11H15ClN2O5

分子量

分子量 290.7

溶解度

H2O : 250 mg/mL (859.99 mM)

储存条件

Store at -20°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride which is a nicotinamide adenine dinucleotide (NAD[+]) precursor vitamin. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements[1]. SIRT1 SIRT3

Nicotinamide riboside chloride (0.5 nM; 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1]. Western Blot Analysis[1] Cell Line: HEK293T cells

Chronic Nicotinamide riboside chloride (p.o.; 400 mg/kg/day; for 16 weeks) supplementation increases plasma and intracellular NAD[+] content in a tissue-specific manner[1]. Animal Model: 10-week-old C57Bl/6J mice[1]

[1]. Cantó C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838-47.

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