性能参数

产品名称

Iniparib (BSI-201)

规格

10mM (in 1mL DMSO) 10mg 50mg 200mg

货号

GOY-Y3714

 含量

>98.00%

CAS

160003-66-7

别名

BSI201,BSI 201

化学名

4-iodo-3-nitrobenzamide

分子式

C7H5IN2O3

分子量

分子量 292.03

溶解度

≥ 103.4 mg/mL in DMSO, ≥ 24.3 mg/mL in EtOH with ultrasonic and warming

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Iniparib, previously named BSI-201, is an intravenously administered PARP1 inhibitor, which either alone or in combination with chemotherapy, has important antitumor activity in studies in vitro and in vivo. It is active against a broad range of cancer cells in culture, including drug resistant cell lines. Iniparib has been reported to be a prodrug whose C-nitroso metabolite, 4-iodo-3-nitrosobenzamide, selectively kills tumor cells by oxidizing the zinc finger of PARP-1 resulting in ejection of zinc and inhibition of PARP activity.

2-二苯基膦苯甲酸  17261-28-8  3,4-二羟基苯腈  17345-61-8

3-苯甲?；┧嵋阴? 17450-56-5  5-氨基-2-甲氧基吡啶-4-羧酸  183741-91-5

(R)-(+)-1,1'-联-2-萘胺  18741-85-0  4-叔丁氧羰基氨基-4-氨基甲?；∷? 18800-74-3

2-氟-3-甲基-5-硝基吡啶  19346-46-4  4-氨基-3-氯吡啶  19798-77-7

双(2-氨基苯基)二硫  1141-88-4  四丙基高钌酸铵  1146

BI 6896481mg 5mg 10mg 25mg>98.00%Cas No. 1633009-87-6C16H18N4O2

BVT 27335mg 10mg 50mg 100mg>98.00%Cas No. 376640-41-4C17H21ClN4O3S2

Bromoenol lactone5mg 10mg 25mg 50mg>98.00%Cas No. 88070-98-8C16H13BrO2

CCT0181591mg 5mg 10mg 50mg>98.00%Cas No. 171009-07-7C20H20N2O4

CGP-531531mg 5mg 10mg 20mg>98.00%Cas No. 149281-19-6C23H33N3O2