653-47 hydrochloride
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产品名称:
653-47 hydrochloride
产品型号:
GOY-Y3755
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-09
简单介绍
653-47 hydrochlorideDMSO : 250 mg/mL (613.81 mM; Need ultrasonic)
653-47 hydrochloride
的详细介绍
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性能参数
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产品名称
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653-47 hydrochloride
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规格
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5 mg 10 mg 25 mg 50 mg 100 mg
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货号
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GOY-Y3755
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含量
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>98.00%
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CAS
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1224567-46-7
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别名
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N/A
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化学名
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N/A
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分子式
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C20H20Cl2N2O3
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分子量
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分子量 407.29
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溶解度
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DMSO : 250 mg/mL (613.81 mM; Need ultrasonic)
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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653-47 hydrochloride, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 hydrochloride is also a very weak CREB inhibitor with IC50 of 26.3 μM[1].
653-47 (5-10 μM) synergistically inhibits CREB-mediated gene transcription with 666-15[1].
[1]. Xie F, et al. Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-Mediated Gene Transcription with 666-15. J Med Chem. 2019;62(24):11423-11429.
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