Glucose-conjugated MGMT inhibitor
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产品名称:
Glucose-conjugated MGMT inhibitor
产品型号:
GOY-Y3784
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-09
简单介绍
Glucose-conjugated MGMT inhibitorDMSO: 100 mg/mL (162.20 mM)
Glucose-conjugated MGMT inhibitor
的详细介绍
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性能参数
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产品名称
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Glucose-conjugated MGMT inhibitor
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规格
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5mg 10mg 50mg 100mg 200mg
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货号
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GOY-Y3784
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含量
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>98.00%
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CAS
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382607-78-5
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别名
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N/A
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化学名
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N/A
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分子式
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C24H34BrN5O7S
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分子量
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分子量 616.53
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溶解度
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DMSO: 100 mg/mL (162.20 mM)
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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Glucose-conjugated MGMT inhibitor is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. MGMT|32 nM (IC50)
Glucose-conjugated MGMT inhibitor (O6BTG-octylglucoside) is a potent and non-toxic MGMT inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells[1].
[1]. Jost Reinhard, et al. Inactivation of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors. Int.J.Cancer. (2001) 93,373-379.
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