商品属性：
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产品名称
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phospho C-Myc (Thr58 / Ser62)抗体
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英文名称
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phospho C-Myc (Thr58 / Ser62)
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K0177
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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肿瘤 细胞生物 信号转导 干细胞 生长因子和** 转录调节因子
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蛋白细胞定位
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细胞核
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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The protein encoded by this e is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target es. Mutations, overexpression, rearrangement and translocation of this e have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this e. [provided by RefSeq, Jul 2008].
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