商品属性：
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产品名称
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phospho-Cortactin (Tyr421)抗体
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英文名称
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phospho-Cortactin (Tyr421)
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1340
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Cow, Horse, Rabbit
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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肿瘤 细胞生物 信号转导 细胞粘附分子
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蛋白细胞定位
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细胞浆
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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This e is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This e has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this e contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this e. [provided by RefSeq].
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