商品属性：
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产品名称
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phospho-MAP4K4 (Ser631)抗体
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英文名称
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phospho-MAP4K4 (Ser631)
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1576
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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肿瘤 信号转导 转录调节因子 激酶和磷酸酶
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蛋白细胞定位
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细胞浆
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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MAP4K4 (Mito-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive e expression, adipoesis, and insulin stimulated glucose transport.
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