产品名称

phospho-PLB (Ser16+Thr17)抗体

英文名称

phospho-PLB (Ser16+Thr17)

产品规格

50ul  100ul 200ul 

产品货号

GOY-01K1936

产品分类

抗体 / 一抗

交叉反应

Human, Mouse, Rat, Dog, Pig, Cow, Sheep

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

标记

Unconjugated

抗体来源

Rabbit

抗体类型

Polyclonal

研究领域

心血管  信号转导 转录调节因子 通道蛋白 细胞表面分子 线抗体

蛋白细胞定位

细胞浆,细胞膜

纯化方法

affinity purified by Protein A

性状

Liquid

浓度

1mg/ml

储存液

 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

发货地

上海

背景资料

Defects in PLN are the cause of cardiomyopathy dilated type 1P (CMD1P) . Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Defects in PLN are the cause of cardiomyopathy familial hypertrophic type 18 (CMH18) . CMH18 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.