商品属性:
产品名称
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Minibrain抗体
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英文名称
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Minibrain
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K0830
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产品分类
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抗体 / 一抗
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交叉反应
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Fruit Fly
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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昆虫
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蛋白细胞定位
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细胞核
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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This e encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This e is a homolog of Drosophila mnb (minibrain) e and rat Dyrk e. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate e for learning defects associated with Down syndrome. Alternative splicing of this e erates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008]
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