商品属性：
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产品名称
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HIV gp160抗体
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英文名称
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HIV gp160
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K0099
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产品分类
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抗体 / 一抗
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交叉反应
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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**及病毒
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蛋白细胞定位
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细胞膜
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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The attachment of enveloped viruses to cells and the fusion of viral and cellular membranes are critical early events in the HIV viral infection. This process is mediated by envelope glycoproteins (gp) on the surface of the virus. The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein, gp160, is proteolytically cleaved into gp120 and gp41, which remain noncovalently associated with one another. gp120 is one of the proteins that forms the envelope of HIV. gp120 projects from the surface of HIV and binds to the CD4 molecule on helper T cells. gp120 has been a logical experimental HIV vaccine because the outer envelope is the first part of the virus that encounters antibody. gp41 is embedded in the outer envelope of HIV that anchors gp120. gp41 also plays a key role in HIV's infection of CD4+ T cells by facilitating the fusion of the viral and cell membranes. The nomenclature of the gp proteins describes their respective molecular masses (e.g., gp160, gp120, gp41).
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